Most Recent Flipbooks
PBI-4050 promotes hepatic stellate cell autophagymitophagy and restores a quiescent-like phenotype
PBI-4050 Improves Metabolic Regulation and Diabetic Nephropathy through Reduction of ER Stress, Pro-Inflammatory/Fibrotic Markers, Galectin-
PBI-4050 reduces systemic inflammation, electrolyte disturbances and renal injury in mice with sepsis-induced acute kidney injury
PBI-4050 exerts anti-inflammatory and anti-fibrotic effects in several diabetic and non-diabetic models of kidney injury through modulation of GPR40 and GPR84 fatty acid receptors.
PBI-4050 decreases adenine-induced tubulointerstitial injury and er-stress; implications of the GPR40 receptor
The aim of this study was to further examine the effects of PBI-4050 in both WT and GPR40 activation-/- mice on adenine-induced tubulointerstitial injury, anemia and the unfolded protein response path
PBI-4050 Improves Metabolic Regulation and Diabetic Nephropathy through Reduction of ER Stress, Pro-Inflammatory/Fibrotic Markers, Galectin-
These results suggest that PBI-4050 is a strong potential candidate for the treatment of metabolic diseases and related diabetic nephropathy.