What Does this Study Demonstrate?
This study demonstrates that PBI-4050:
- Improves triglyceride and glucose metabolism
- Reduces collagen and galectin-3 deposition in WAT and kidney
- Reduces ER stress and pro-inflammatory/fibrotic markers in kidney
These results suggest that PBI-4050 is a strong potential candidate for the treatment of metabolic diseases and related diabetic nephropathy.