PBI-4050 Improves Metabolic Regulation and Diabetic Nephropathy through Reduction of ER Stress, Pro-Inflammatory/Fibrotic Markers, Galectin-

June 22, 2018

What Does this Study Demonstrate?

This study demonstrates that PBI-4050:

  • Improves triglyceride and glucose metabolism
  • Reduces collagen and galectin-3 deposition in WAT and kidney
  • Reduces ER stress and pro-inflammatory/fibrotic markers in kidney

These results suggest that PBI-4050 is a strong potential candidate for the treatment of metabolic diseases and related diabetic nephropathy.